Antimicrobial Susceptibility Testing for Polymyxins: Challenges, Issues, and Recommendations

Antimicrobial susceptibility testing issues relating to EARSS

Ontario’s Future Prosperity: Issues, Challenges and Recommendations

Ontario as a small open economy has many fiscal levers and programs that could create and enhance its distinctive advantages in the North American global economies. Better tax policies and public services can encourage work, investment and more effective use of resources. In this paper, we examine expenditure and tax policies for Ontario in comparison to some other provinces and the United Stat...

Antimicrobial susceptibility testing: a primer for clinicians.

Appropriate use of antimicrobials in health care continues to be a challenge. Reliable and reproducible antimicrobial susceptibility testing methods are necessary to provide the clinician with valuable information that can be translated into positive clinical outcomes at the bedside. However, there are nuances with these testing methods that, if unrecognized, could lead to misinterpretation of ...

High-throughput microarray for antimicrobial susceptibility testing

We describe the development of a novel, high-throughput, nano-scale microarray platform for antimicrobial susceptibility testing (AST). The platform allows to process 480 samples at 50 nL volume on a single chip, analyze by fluorescence read-out with an easy dunk-and-rinse step, and the ability to process multiple samples and chips simultaneously. We demonstrate the applicability of this chip f...

Antimicrobial Susceptibility Testing of Cefoperazone

Cefoperazone is a new cephalosporin with a very wide spectrum of activity, including activity against Pseudomonas aeruginosa. It has less activity on enterococci and Acinetobacter. Of the 459 selected bacterial strains tested in this study, only 1.5% (7 strains and 6 genera) had minimum inhibitory concentrations of >128 ,ug/ml. For a minimum inhibitory concentration breakpoint of <32 p.g/ml (su...